Anafranil Drug Interactions

Anafranil Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Anafranil is combined with any of the drugs listed above.
 
Alcohol
Anafranil may enhance the effects of alcohol. Be sure to talk with your healthcare provider about drinking alcohol while taking Anafranil.
 
Anticholinergic Medications
Taking Anafranil with anticholinergic medications may increase your risk of side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines. Therefore, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.
 
Arrhythmia Medications
Taking Anafranil with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of Anafranil in your blood, increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.
 
Barbiturates
Taking Anafranil with barbiturates can increase the risk of side effects of both Anafranil and barbiturates, such as drowsiness or dizziness. It is also possible that taking these medications together could decrease the level of Anafranil in your blood, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these medications.
 
Cimetidine (Tagamet)
Taking Anafranil with cimetidine can increase the level of Anafranil in your blood, increasing your chance of side effects. Your healthcare provider may need to decrease your Anafranil dosage or suggest an alternative to cimetidine.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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