Drug Combinations With Anafranil to Avoid

Thyroid Medications
Taking Anafranil with thyroid medications can increase your risk of Anafranil side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Tramadol
Combining Anafranil with tramadol may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tricyclic Antidepressants
Taking Anafranil with other tricyclic antidepressants can increase your risk of side effects, including serotonin syndrome. Your healthcare provider may need to adjust your dose of these medications.
 
Triptans
Combining Anafranil with a triptan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tryptophan
Combining Anafranil with tryptophan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Warfarin (Coumadin, Jantoven)
Taking warfarin with Anafranil can increase the effects of warfarin, perhaps increasing your risk of bleeding. Your healthcare provider may need to monitor you more closely and adjust your warfarin dosage.
 

Final Thoughts on Anafranil Drug Interactions

It is possible that not every Anafranil drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions with Anafranil that may apply to your situation. 
 
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Anafranil Drug Information

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