BuSpar Drug Interactions: An Overview
BuSpar® (
buspirone hydrochloride) can potentially interact with a number of other medications, especially those that affect the brain. Some of the medicines that may lead to BuSpar drug interactions include:
- Certain antibiotics or antifungals, such as:
o Isoniazid (Nydrazid®)
o Itraconazole (Sporanox®)
o Ketoconazole (Nizoral®)
o Telithromycin (Ketek®)
- Certain seizure medications, such as:
o Fosphenytoin (Cerebyx®)
o Phenobarbital (Luminal®)
o Pentobarbital (Nembutal®)
- Monoamine oxidase inhibitors (MAOIs), such as:
- Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®)
Grapefruit juice can also interact with BuSpar. Studies have shown that it can increase the level of BuSpar in your blood, increasing your risk of side effects. It is best to avoid drinking large amounts of grapefruit juice while taking BuSpar.