Safety Concerns When Taking Clomipramine With Other Drugs
Clomipramine and Serotonin Syndrome
Several of the known interactions with clomipramine are related to a potentially dangerous group of symptoms known as serotonin syndrome. Such symptoms might include:
- Fast heartbeat
- Feeling faint
- Muscle spasm
- Difficulty walking
Clomipramine Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when clomipramine is combined with any of the drugs listed above.
Clomipramine may enhance the effects of alcohol. Be sure to talk with your healthcare provider about drinking alcohol while taking clomipramine.
Taking clomipramine with anticholinergic medications may increase your risk of side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines. Therefore, do not treat yourself for the common cold, a cough, or allergies without first talking to your healthcare provider.
Taking clomipramine with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of clomipramine in your blood, increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.