Clomipramine Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
clomipramine is combined with any of the drugs listed above.
Alcohol
Clomipramine may enhance the effects of alcohol. Be sure to talk with your healthcare provider about drinking alcohol while taking clomipramine.
Anticholinergic Medications
Taking clomipramine with anticholinergic medications may increase your risk of side effects. Talk to your healthcare provider before using these medications together, as your dosages may need to be reduced. Since some of these types of medicines are found in over-the-counter medicines. Therefore, do not treat yourself for the
common cold, a cough, or
allergies without first talking to your healthcare provider.
Arrhythmia Medications
Taking clomipramine with arrhythmia medications can increase your risk of a dangerous arrhythmia called QT prolongation. Also, certain arrhythmia medications can increase the level of clomipramine in your blood, increasing your risk of side effects. Talk to your healthcare provider before taking these medications together.
Barbiturates
Taking clomipramine with barbiturates can increase the risk of side effects of both clomipramine and barbiturates, such as drowsiness or dizziness. It is also possible that taking these medications together could decrease the level of clomipramine in your blood, perhaps making it less effective. Your healthcare provider may need to adjust your dose of these medications.
Cimetidine (Tagamet)
Taking clomipramine with
cimetidine can increase the level of clomipramine in your blood, increasing your chance of side effects. Your healthcare provider may need to decrease your clomipramine dosage or suggest an alternative to cimetidine.
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