Combining Clomipramine With Other Medicines

St. John's Wort
Combining clomipramine with St. John's wort may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Thyroid Medications
Taking clomipramine with thyroid medications can increase your risk of clomipramine side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Tramadol
Combining clomipramine with tramadol may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tricyclic Antidepressants
Taking clomipramine with other tricyclic antidepressants can increase your risk of side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Triptans
Combining clomipramine with a triptan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tryptophan
Combining clomipramine with tryptophan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Warfarin (Coumadin, Jantoven)
Taking warfarin with clomipramine can increase the effects of warfarin, perhaps increasing your risk of bleeding. Your healthcare provider may need to monitor you more closely and adjust your warfarin dosage.
 

Final Thoughts on Drug Interactions With Clomipramine

It is possible that not every clomipramine drug interaction was discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions with clomipramine that may apply to your situation.
 
 
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