Drug Interactions With Clonazepam

Clonazepam Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when clonazepam is combined with any of the drugs listed above.
 
Alcohol
Combining alcohol with clonazepam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. It is best to avoid alcohol while taking clonazepam (see Klonopin and Alcohol).
 
Anesthetics
Combining anesthetics with clonazepam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure your healthcare providers know you are taking clonazepam before you undergo any surgical procedure.
 
Antidepressant Medications
Combining an antidepressant with clonazepam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking clonazepam with an antidepressant, as you may need to be monitored more closely.
 
Antipsychotic Medications
Combining an antipsychotic medication with clonazepam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking clonazepam with an antipsychotic medication.
 
Barbiturates
Combining a barbiturate with clonazepam can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking clonazepam with a barbiturate.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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