Discussing Clorazepate With Your Doctor and How It Works
What Should I Tell My Healthcare Provider Before Taking Clorazepate?You should talk with your healthcare provider prior to taking this medication if you have:
- A history of drug or alcohol abuse (see Tranxene and Alcohol)
- Liver disease, including liver failure or cirrhosis
- Kidney disease, including kidney failure (renal failure)
- Any allergies, including allergies to food, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Tranxene and Pregnancy)
- Breastfeeding (see Tranxene and Breastfeeding).
Make sure to tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Clorazepate to learn more, including information on who should not take the drug.)
How Does It Work?Clorazepate is part of a group of medicines known as benzodiazepines. Benzodiazepines have several different effects on the body, including:
All benzodiazepines can have these effects to some degree, depending on the specific medication and the dosage. They work in the brain by enhancing the effects of gamma-aminobutyric acid (GABA), a brain chemical that is naturally calming. GABA can slow down or stop certain nerve signals in the brain. This is why clorazepate and other benzodiazepines are known as mild tranquilizers, sedatives, or central nervous system depressants (CNS depressants).