Drug Interactions With Clorazepate

Drug interactions with clorazepate can occur if the drug is combined with anesthetics, narcotics, alcohol, or barbiturates. These interactions may cause difficulty breathing, severe drowsiness, and memory loss, among other things. Because drug interactions with clorazepate can be quite serious -- even life threatening -- tell your healthcare provider about all medicines you are taking, including non-prescription ones.

Drug Interactions With Clorazepate: An Overview

 Clorazepate (Tranxene®) can potentially interact with several other medications, especially those that affect the brain. Some of the medicines that may lead to drug interactions with clorazepate include:
 
 
  • Barbiturates, including:
     
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
 
 
 
  • Seizure medications
  • Sleep medications.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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