Alcohol and Compazine

Compazine and alcohol may potentially be a dangerous combination. It is generally recommended that people with mental illnesses -- such as those that Compazine is commonly used to treat -- avoid drinking alcohol. Compazine side effects, such as drowsiness or low blood pressure, may be more likely to occur if you drink alcohol while taking the medication.

 

Can I Drink Alcohol While Taking Compazine?

According to the Compazine® (prochlorperazine maleate) prescription information, drinking alcohol while on Compazine is not recommended. Combining alcohol and Compazine can increase the chances and severity of several Compazine side effects. Additionally, for many people with mental illness, it is usually recommended that alcohol be avoided.
 

Alcohol and Compazine Side Effects

Drinking alcohol may increase your risk of certain Compazine side effects, such as drowsiness or low blood pressure (when sitting or standing up). You may also be more sensitive to the effects of alcohol if you are taking Compazine. You may not be able to safely drink as much alcohol as you were used to drinking in the past.
 
Compazine is approved to treat schizophrenia, anxiety, or severe nausea and vomiting. Generally, it is best for people with mental illnesses to avoid drinking alcohol. Alcohol may worsen mental illness and is often a form of "self-medication."
 

Talking With Your Healthcare Provider About Alcohol and Compazine

Although it is not recommended that you drink alcohol while taking Compazine, you should not be afraid to discuss your alcohol consumption with your healthcare provider. Together, you and your healthcare provider can make a shared decision about Compazine and alcohol for your particular situation. If you do drink, your healthcare provider can also suggest ways to help you stop drinking.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;