Compazine and Dry Mouth

There are a number of possible side effects that may occur with Compazine, and dry mouth appears to be one of them. If you are taking Compazine and dry mouth occurs, you can try avoiding drinks with caffeine, sipping water or sugarless drinks often, and avoiding tobacco or alcohol, among other things. If your dry mouth symptoms don't improve, your healthcare provider can also recommend treatment or adjust your Compazine dosage.

 

Does Compazine Cause a Dry Mouth?

Compazine® (prochlorperazine maleate) is a prescription medicine used to treat schizophrenia, anxiety, and severe nausea and vomiting. Like other medicines, it can cause side effects. One of these possible side effects of Compazine is a dry mouth.
 

Recommendations for Compazine and Dry Mouth

If you are taking Compazine and dry mouth becomes a problem, there are a number of things that you can do.
 Some of these suggestions include:
 
  • Sipping water or sugarless drinks often.
     
  • Sipping water or sugarless drinks during meals. This will make chewing and swallowing easier. It may also improve the taste of food.
     
  • Avoiding drinks with caffeine, such as coffee, tea, and some sodas. Caffeine can dry out the mouth.
     
  • Avoiding tobacco or alcohol. They dry out the mouth.
     
  • Using a humidifier at night.
     
  • Being aware that spicy or salty foods may cause pain in a dry mouth.
     
  • Chewing sugarless gum or sucking on sugarless hard candy to stimulate saliva flow; cinnamon- or mint-flavored candies are good choices.
     
(Compazine and Dry Mouth Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;