Compazine Drug Interactions

When alcohol or medicines like barbiturates, propranolol, or seizure medications are taken together with Compazine, drug interactions can potentially occur. These interactions can affect the levels of some medications in your blood and increase your risk of sedation and other problems. To help prevent Compazine drug interactions from occurring, be sure to talk with your pharmacist or healthcare provider about any interactions that may apply to you.

 

An Introduction to Compazine Drug Interactions

Compazine® (prochlorperazine maleate) can potentially interact with a number of other medicines. Some of these medicines that may lead to Compazine interactions include:
 
  • Alcohol
  • Barbiturates, including:

 

    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)

 

  • Narcotics or opiates such as morphine or oxycodone (Oxycontin®)
  • Propranolol (Inderal®, Inderal LA®, InnoPran XL®)
  • Seizure medications
  • Warfarin (Coumadin®, Jantoven®).
     

Compazine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Compazine is combined with any of the drugs listed above.
(Compazine Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;