Doxepin (Sinequan^®, Silenor^®) is a prescription drug licensed to treat depression and anxiety. It is also approved to treat insomnia. By affecting certain chemicals in the brain (serotonin and norepinephrine), the medication can significantly reduce depression symptoms and anxiety. Potential side effects of doxepin may include drowsiness, dry mouth, or difficulty urinating. Brand-name doxepin is no longer being manufactured, but a generic version is currently available.

(Click Doxepin for more information on the various doxepin strengths available, suggestions for when and how to take the medication, and a list of important precautions and warnings to be aware of before starting treatment.)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD

Last reviewed by: Kristi Monson, PharmD

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