Doxepin Side Effects
Common side effects of doxepin include drowsiness, weight gain, and dry mouth. In most cases, side effects are minor and either require no treatment or can easily be treated by a healthcare provider. However, certain side effects are more serious and should be reported to your healthcare provider right away, including signs of an allergic reaction, fast heart rate, and any breast changes.
As with any medicine, there are possible side effects with doxepin hydrochloride (Sinequan®, Silenor®). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate the antidepressant well. When people do develop doxepin side effects, in many cases they are minor, meaning they require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, possible side effects with doxepin. Your healthcare provider can discuss a more complete list with you.)
Doxepin has been studied thoroughly in clinical trials in which the side effects seen with a group of people taking the drug are documented and compared to another group not taking the medicine. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
- Dizziness or lightheadedness
- Difficulty urinating
- Dry mouth (see Doxepin and Dry Mouth)
- Weight gain (see Sinequan and Weight Gain)
- Changes in libido (sex drive)
- Changes in blood sugar levels
- Increased sweating.
Withdrawal side effects have been reported in people who have stopped taking doxepin suddenly (see Doxepin Withdrawal).
In clinical trials, low-dose doxepin (used to treat insomnia) was reported to cause the following common side effects: