Precautions and Warnings With Doxepin

To minimize risks and help ensure a safe treatment process, make sure you are aware of all the precautions and warnings with doxepin before you start the drug. Warnings include using caution when you are driving or operating machinery while taking the drug, looking out for certain drug interactions, and possibly avoiding the medicine while you are breastfeeding. Doxepin is not suitable for everyone; do not take the antidepressant if you are allergic to any components of the medicine, have trouble passing urine, or have glaucoma.

Doxepin HCl

Doxepin: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking

doxepin hydrochloride (Sinequan^®, Silenor^®) if you have:

Bipolar disorder or a family history of bipolar disorder (also known as manic depression)
Schizophrenia
A history of suicide attempts or suicidal thoughts
Severe anxiety or agitation
Had a recent heart attack
Heart problems, including heart disease
Hyperthyroidism (overactive thyroid)
Seizures or epilepsy
Glaucoma
Liver disease, such as liver failure, cirrhosis, or hepatitis
Sleep apnea
Bladder problems or difficulty passing urine
An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
Any allergies, including allergies to foods, dyes, or preservatives.

Also, let your healthcare provider know if you:

Are pregnant or thinking of becoming pregnant
Are breastfeeding
Drink alcohol regularly.

Make sure to tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

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