Precautions and Warnings With Doxepin
To minimize risks and help ensure a safe treatment process, make sure you are aware of all the precautions and warnings with doxepin before you start the drug. Warnings include using caution when you are driving or operating machinery while taking the drug, looking out for certain drug interactions, and possibly avoiding the medicine while you are breastfeeding. Doxepin is not suitable for everyone; do not take the antidepressant if you are allergic to any components of the medicine, have trouble passing urine, or have glaucoma.
You should talk with your healthcare provider prior to taking doxepin hydrochloride (Sinequan®, Silenor®) if you have:
- Bipolar disorder or a family history of bipolar disorder (also known as manic depression)
- A history of suicide attempts or suicidal thoughts
- Severe anxiety or agitation
- Had a recent heart attack
- Heart problems, including heart disease
- Hyperthyroidism (overactive thyroid)
- Seizures or epilepsy
- Liver disease, such as liver failure, cirrhosis, or hepatitis
- Sleep apnea
- Bladder problems or difficulty passing urine
- An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant
- Are breastfeeding
- Drink alcohol regularly.
Make sure to tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.