How Effective Is Duloxetine?
EffectsThere have been several studies looking at the effects of duloxetine on a variety of conditions.
Duloxetine for Depression
Four studies have shown duloxetine to be effective for depression treatment in adults. In these studies, people taking duloxetine had more improvement in their depression symptoms, compared to those not taking duloxetine.
Duloxetine for Neuropathy
Duloxetine has also been studied for neuropathic pain (nerve pain) in people with peripheral diabetic neuropathy. These studies included people with either type 1 or type 2 diabetes who had been experiencing diabetic neuropathy pain for at least six months. People taking duloxetine were more likely to have half as much pain as before, compared to those not taking duloxetine.
Duloxetine for Anxiety
Studies have also shown duloxetine to be effective for treating generalized anxiety disorder (GAD). People taking duloxetine had greater improvements in their anxiety symptoms, compared to those not taking duloxetine.
Duloxetine for Fibromyalgia
Studies indicate that Cymbalta can help reduce fibromyalgia pain. Duloxetine was more effective than a placebo (a "sugar pill") for relieving pain, even in people who did not have depression along with fibromyalgia (although it was most effective in people that had depression).