Common Duloxetine Side Effects
Duloxetine has been studied thoroughly in clinical trials, in which the side effects in a group of people taking the drug are documented and compared to another group not taking the medicine. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
In these studies, the most common side effects of duloxetine included:
- Nausea -- in up to 30 percent of people
- Drowsiness -- up to 21 percent
- Headaches -- up to 20 percent
- Dry mouth -- up to 18 percent (see Cymbalta and Dry Mouth)
- Dizziness -- up to 17 percent
- Insomnia -- up to 16 percent (see Cymbalta and Insomnia)
- Constipation -- up to 15 percent
- Fatigue -- up to 15 percent
- Diarrhea -- up to 13 percent
- Loss of appetite -- up to 11 percent
- Sore throat or runny nose -- up to 9 percent
- Weakness -- up to 8 percent
- Sweating -- up to 8 percent
- Vomiting -- up to 8 percent
- A decreased sex drive (libido) -- up to 7 percent (see Sexual Side Effects of Cymbalta)
- Upper respiratory tract infection (such as the common cold) -- up to 7 percent
- Coughing -- up to 6 percent.
Other common side effects (occurring in 2 to 5 percent of people) included:
- Shakiness (tremors)
- Frequent urination
- Muscle pain
- Sexual side effects, including:
- Indigestion or heartburn
- Seasonal allergies
- Muscle spasms
- Taste changes
- Abnormal dreams
- Cough.
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