Effexor XR and Weight Loss

In previous studies, weight loss was most commonly seen in people taking Effexor XR for depression and was least commonly seen in people taking the drug for social anxiety disorder or generalized anxiety disorder. Weight loss can also occur in children and teens who take Effexor. In fact, in previous studies, children and adolescents lost an average of one pound when first beginning treatment with the medication. If you are taking Effexor XR and weight loss occurs, talk with your healthcare provider.

 

Effexor XR and Weight Loss: An Introduction

Weight loss is a common side effect of Effexor XR® (venlafaxine XR), occurring in up to 7 percent of people who take the drug. In previous studies, weight loss was most commonly seen in people with depression (7 percent) and was least commonly seen in people with social anxiety disorder or generalized anxiety disorder (3 percent). On average, people lose about one to two pounds when they begin taking Effexor XR. On rare occasions, people taking Effexor XR have significant weight loss that requires a discontinuation of the medication.
 

Effexor XR and Weight Loss in Children and Adolescents

Although Effexor XR is not approved for people under the age of 18, it can be used "
 off-label" in children and adolescents. For children and adolescents taking Effexor XR, weight loss can also occur. In previous studies, children and adolescents lost an average of one pound when they began treatment with Effexor XR. However, there were a number of children and adolescents who saw substantial weight loss while on Effexor XR. In fact, 18 percent of children who took Effexor XR saw weight loss greater than 3.5 percent of their body weight.
 
For most children and adolescents who take Effexor XR, weight loss is regained after six to nine months of therapy. However, it is recommended that the height and weight of children and adolescents who are taking Effexor XR be regularly monitored.
 
(Effexor XR and Weight Loss Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;