Drug Combinations WIth Effexor XR to Avoid

Tricyclic Antidepressants
Taking Effexor XR with tricyclic antidepressants can increase the level of tricyclic antidepressants in your blood. If you are taking these drugs together, your healthcare provider may need to reduce your dose of the tricyclic antidepressant.
 
Triptans
Taking Effexor XR with a triptan can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Tryptophan
Taking Effexor XR with tryptophan can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 

Final Thoughts on Effexor XR Interactions

It is possible that not all possible Effexor XR drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions with Effexor XR that may apply to you.
 
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Effexor XR Drug Info

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