Taking Other Medicines With Escitalopram

Fentanyl
Combining escitalopram with fentanyl may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Intravenous Methylene Blue
Taking escitalopram with intravenous methylene blue can increase your chance of developing dangerous side effects, including serotonin syndrome. Do not take these medications together.
  
Ketoconazole (Nizoral)
Taking ketoconazole with escitalopram may decrease the level of ketoconazole in your blood, perhaps making it less effective. If you are taking these drugs together, your healthcare provider may need to increase your ketoconazole dose.
 
Linezolid (Zyvox)
Taking escitalopram with linezolid can cause a group of symptoms called serotonin syndrome. These symptoms can include confusion, hallucinations, fast heartbeat, feeling faint, a fever, sweating, muscle spasms, difficulty walking, and diarrhea. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be very dangerous.
 
Lithium (Eskalith, Lithobid)
Taking escitalopram with lithium can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
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