Fluoxetine Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
fluoxetine is combined with any of the drugs listed above.
Alprazolam
Taking fluoxetine with
alprazolam can increase the level of alprazolam in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your dose of alprazolam.
Aspirin
Taking fluoxetine and aspirin together can increase your risk of stomach bleeding. Talk to your healthcare provider before taking aspirin and fluoxetine together.
Certain Antipsychotic Medications
Fluoxetine can increase the level of certain
antipsychotic medications in your blood and can increase your risk of side effects. Your healthcare provider may need to lower your dose of antipsychotic medicine.
Pimozide and
thioridazine should never be taken with fluoxetine. In fact, you should not take thioridazine if you have taken fluoxetine within the past five weeks.
Certain Seizure Medications
Taking fluoxetine with certain
seizure medications (
carbamazepine and
phenytoin) can increase the level of the
seizure medication in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your dose of seizure medication.
Diazepam (Valium)
Taking fluoxetine with
diazepam can increase the level of diazepam in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your dose of diazepam.
Digoxin (Digitek, Lanoxin)
Taking fluoxetine and
digoxin together can increase your risk of
digoxin side effects. Your healthcare provider may need to adjust your digoxin dose when starting or stopping fluoxetine.
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