Fluvoxamine Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when
fluvoxamine is combined with any of the drugs listed above.
Alcohol
It is not recommended that you drink alcohol while taking fluvoxamine. Combining alcohol and fluvoxamine together may cause unwanted side effects
(see Alcohol and Luvox).
Alosetron (Lotronex)
Taking alosetron and fluvoxamine together can greatly increase the level of alosetron in your blood, increasing your risk of side effects. It is not recommended that you take these two medications together.
Antipsychotic Medications
Taking fluvoxamine with
antipsychotic medications may increase your risk of neuroleptic malignant syndrome (NMS). Symptoms of NMS can include a fever, muscle tension, changes in heart rate and
blood pressure, and mental changes (such as confusion). Tell your healthcare provider right away if you are having symptoms of NMS.
Aspirin
Taking fluvoxamine and aspirin together can increase your risk of stomach bleeding. Talk with your healthcare provider before taking aspirin and fluvoxamine together.
Certain Benzodiazepines
Taking fluvoxamine with certain benzodiazepines can raise the level of benzodiazepine medication in your blood, increasing your risk of side effects. Talk with your healthcare provider before taking these medications together. Some benzodiazepines should not be taken with fluvoxamine, while others can be used at lower dosages.
Cisapride (Propulsid)
Taking fluvoxamine with cisapride can increase your risk of a dangerous irregular heart rhythm (arrhythmia) called QT prolongation. These two medications should not be taken together.
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