Combining Fluvoxamine With Other Medicines

Tizanidine (Zanaflex)
Taking tizanidine and fluvoxamine together can raise the level of tizanidine in your blood, increasing your risk of side effects. These two medications should not be taken together.
 
Tramadol (Rybix ODT, Ryzolt, Ultram, Ultram ER) or Tramadol and Acetaminophen (Ultracet)
Taking fluvoxamine with tramadol can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Tricyclic Antidepressants
Taking fluvoxamine with tricyclic antidepressants can increase the levels of tricyclic antidepressants in your blood. If you are taking these drugs together, your healthcare provider may need to reduce your dose of the tricyclic antidepressant.
 
Triptans
Taking fluvoxamine with a triptan can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Tryptophan
Taking fluvoxamine with tryptophan can cause a group of symptoms called serotonin syndrome. Talk with your healthcare provider before taking these medications together. Call your healthcare provider right away if you have any symptoms of serotonin syndrome (see above), as it can be very dangerous.
 
Warfarin
Taking fluvoxamine and warfarin together may increase your risk of bleeding, especially in the stomach or intestines. If you are taking these drugs together, your healthcare provider may choose to monitor you more closely when you are starting or stopping fluvoxamine.
 
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