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Some people may experience side effects with Sarafem, and weight loss appears to be one of the side effects that can occur. If you are taking Sarafem and weight loss becomes a problem, be sure to let your healthcare provider know.

An Overview of Sarafem and Weight Loss

Sarafem® (fluoxetine hydrochloride) is a prescription medication used to treat premenstrual dysphoric disorder (PMDD). There are a number of possible side effects of Sarafem. Weight loss appears to be one of them. For some people, this may be a good thing. For a lot of people, though, unintended weight loss can be a problem.
 

How Common Is Weight Loss With Sarafem?

Clinical studies of Sarafem have shown that up to 12 percent of women taking Sarafem experienced significant weight loss (7 percent of their body weight or more). Weight loss was more common in women taking Sarafem 60 mg per day and was less common in women taking Sarafem 20 mg per day. Only 3 percent of women not taking Sarafem experienced significant weight loss.
 

Why Does Sarafem Cause Weight Loss?

It is not entirely clear as to why Sarafem causes weight loss. Sarafem can often cause a loss of appetite and nausea, which may contribute to weight loss. Often, these side effects go away with time.
 
If you are experiencing too much weight loss with Sarafem, be sure to let your healthcare provider know.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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