Niravam Warnings and Precautions

Before taking Niravam, tell your healthcare provider about any other medicines you are taking. Other Niravam warnings and precautions relate to issues such as the safety of taking the drug during pregnancy or while breastfeeding, the risk of dependence and abuse in some people who take this drug, and being aware of those who should not take the medicine at all.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Niravam® (orally disintegrating alprazolam) if you have:
 
  • A history of drug or alcohol abuse
  • Glaucoma
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • Depression or bipolar disorder
  • Lung disease or breathing problems
  • Any allergies, including to foods, dyes, or preservatives.
 
Also, let your healthcare provider know if you are:
 
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
 
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Precautions and Warnings for Niravam

Some warnings and precautions to be aware of prior to taking Niravam include the following:
 
  • This medication can cause physical dependence, which could lead to serious withdrawal symptoms if you stop taking Niravam abruptly. Doses above 4 mg a day and use for longer than 12 weeks may increase the risk for withdrawal symptoms. Do not stop taking this medication suddenly or decrease your dose without talking to your healthcare provider.
 
  • Niravam is a controlled substance because it has a potential for abuse. As a controlled substance, there are special rules and regulations controlling its use. People who take higher doses, who use the medication for a longer period, or who have a history of alcohol or drug abuse have a higher risk for Niravam addiction.
Do not take the drug more frequently or at a higher dose than prescribed. Talk to your healthcare provider if you believe you are developing a problem with Niravam abuse.
  • This product may affect your ability to perform complex tasks requiring mental and motor skills. Taking Niravam with alcohol or other medications that cause drowsiness can increase this effect (see Niravam Drug Interactions for more information). Do not perform activities requiring mental or motor concentration, such as driving a car or operating machinery, until you know how this medication affects you.
 
  • Make sure to tell your healthcare provider if you experience any changes in mood, including depression or an overly excited and elevated mood (termed "mania"). Also, talk to your healthcare provider if you have any thoughts of suicide or of harming yourself while taking this medicine. Based on your individual situation, your healthcare provider can determine if Niravam is the best medication for you.
 
  • Older adults may be more sensitive to the side effects of this medication, including drowsiness and coordination problems. Because of these side effects, older adults who take Niravam may have an increased risk for falls. Older adults should be started on lower doses and maintained on the lowest dose that treats their symptoms (see Niravam Dosage).
 
  • Niravam may be dangerous for people with severe lung disease. Make sure to talk to your healthcare provider about any lung or breathing problems you have before taking this medication.
 
  • Make sure your healthcare provider knows if you have liver or kidney disease, as your body may handle Niravam differently than expected.
 
  • There have been reports of people experiencing unexpected reactions to Niravam that are the opposite of the usual effects. In these cases, people may become restless, agitated, aggressive, or irritable. They may also have difficulty sleeping or may experience hallucinations (seeing or hearing things that are not there).
Talk to your healthcare provider if you notice any of these problems while taking Niravam. People who have certain mental health conditions, a history of aggression, or alcohol or substance abuse problems may be at an increased risk for these reactions.
  • Niravam is a pregnancy Category D medication. This means that the drug may cause harm to an unborn baby if it is used during pregnancy (see Niravam and Pregnancy for more information).
 
  • Niravam passes through breast milk. Therefore, if you are breastfeeding or plan to start, talk with your healthcare provider before taking this drug (see Niravam and Breastfeeding).
 
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Niravam Medication Information

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