Causes of Obsessive-Compulsive Disorder

Causes of obsessive-compulsive disorder are still not fully understood. There is, however, evidence that abnormal functioning of the brain's circuitry may be one of the potential causes. In addition, PET scans show that both behavioral therapy and medication produce changes in the brain in patients with obsessive-compulsive disorder. Family problems or attitudes learned in childhood are not causes of obsessive-compulsive disorder.

 

An Overview of the Causes of Obsessive-Compulsive Disorder

The exact causes of obsessive-compulsive disorder are unknown and are the subject of intense scientific investigation.
 

The Brain and Causes of Obsessive-Compulsive Disorder

There is growing evidence that obsessive-compulsive disorder represents abnormal functioning of brain circuitry, probably involving a part of the brain called the striatum.
 
Brain imaging studies using a technique called positron emission tomography (PET) have compared people with and without obsessive-compulsive disorder. Those with the condition have patterns of brain activity that differ from people with other mental illnesses or people with no mental illness at all.
 
In addition, PET scans show that in patients with obsessive-compulsive disorder, both behavioral therapy and medication produce changes in the striatum. This is graphic evidence that both psychotherapy and medication affect the brain.
 

Can Family Connections Be Causes of Obsessive-Compulsive Disorder?

Obsessive-compulsive disorder is not caused by family problems or by attitudes learned in childhood, such as an inordinate emphasis on cleanliness, or a belief that certain thoughts are dangerous or unacceptable.
 
Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD