Side Effects of Paroxetine Controlled Release

Common Paroxetine Controlled Release Side Effects

Paroxetine controlled release has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and then compared to the side effects that occurred in another group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group not taking the medicine. 
 
In these studies, some of the most common side effects of paroxetine controlled release included:
 
  • Headaches -- in up to 27 percent of people
  • Ejaculation problems -- up to 27 percent of people (see Paxil CR Sexual Side Effects)
  • Nausea -- up to 23 percent of people
  • Drowsiness -- up to 22 percent of people
  • Insomnia -- up to 20 percent of people (see Paxil CR and Insomnia)
  • Weakness -- up to 18 percent of people
  • Diarrhea -- up to 18 percent of people
  • Dry mouth -- up to 18 percent of people (see Paxil CR and Dry Mouth)
  • Dizziness -- up to 14 percent of people
  • Increased sweating -- up to 14 percent of people
  • Constipation -- up to 13 percent of people
  • Indigestion -- up to 13 percent of people
  • A decreased sex drive (libido) -- up to 13 percent of people (see Paxil CR Sexual Side Effects)
  • A loss of appetite -- up to 12 percent of people
  • Female orgasm problems -- up to 10 percent of people
  • Impotence (erectile dysfunction or ED) -- up to 10 percent of people.
     
Other common side effects (occurring in 5 percent to 9 percent of people) included:
 
  • Infections
  • Injuries (trauma)
  • Gas
  • Shakiness (tremors)
  • Nervousness
  • Abdominal pain (stomach pain)
  • Back pain
  • Muscle pain
  • Anxiety
  • Yawning
  • Vision changes.
      
(Side Effects of Paroxetine Controlled Release Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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