Paxil Drug Interactions

Paxil Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Paxil is combined with any of the drugs listed above.
 
Alcohol
The manufacturer of Paxil recommends avoiding alcohol while taking the medication. Combining alcohol and Paxil may cause unwanted side effects (see Alcohol and Paxil).
 
Aspirin
Taking Paxil and aspirin together can increase your risk of stomach bleeding. Talk to your healthcare provider before taking aspirin and Paxil together.
 
Atomoxetine (Strattera)
Paxil can increase the level of Strattera in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your Strattera dosage.
 
Certain Arrhythmia Medications
Taking Paxil with certain arrhythmia medications can increase the level of Paxil or the arrhythmia medication in your blood, increasing your risk of side effects. Your healthcare provider may need to monitor you more closely and may need to adjust your dose of these medications.
 
Certain Seizure Medications
Certain seizure medications (phenobarbital and phenytoin) may decrease the level of Paxil in your blood, perhaps making it less effective. Also, taking Paxil with these medications can lead to increased drowsiness. Your healthcare provider may need to adjust your dose of these medications.
 
Cimetidine (Tagamet)
Taking cimetidine with Paxil can increase the level of Paxil in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your Paxil dose or may suggest an alternative to cimetidine.
Paxil Drug Interactions Article Continues on Next Page >

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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