What You Need to Know About Serotonin Syndrome and Paxil

Paxil and Serotonin Syndrome

Several of the known interactions with Paxil are related to a potentially dangerous group of symptoms known as serotonin syndrome. Such symptoms might include:
  • Confusion
  • Hallucination
  • Fast heartbeat
  • Feeling faint
  • Fever
  • Sweating
  • Muscle spasm
  • Difficulty walking
  • Diarrhea.
Serotonin syndrome usually occurs when people take more than one medication that affects serotonin at the same time. Talk to your healthcare provider before taking these medications together. In many cases, such combinations are still recommended, although with more careful monitoring. Call your healthcare provider right away if you have any of these symptoms, as serotonin syndrome can be dangerous.

Paxil Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Paxil is combined with any of the drugs listed above.
The manufacturer of Paxil recommends avoiding alcohol while taking the medication. Combining alcohol and Paxil may cause unwanted side effects (see Alcohol and Paxil).
Taking Paxil and aspirin together can increase your risk of stomach bleeding. Talk to your healthcare provider before taking aspirin and Paxil together.
Atomoxetine (Strattera)
Paxil can increase the level of Strattera in your blood, increasing your risk of side effects. Your healthcare provider may need to lower your Strattera dosage.
Buspirone (BuSpar)
Because combining Paxil with buspirone may increase the risk of serotonin syndrome, check with your healthcare provider before taking these medications together.
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Paxil Information

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