Third-Trimester Concerns With Sarafem

Sarafem and Third-Trimester Concerns

Sarafem is a selective serotonin reuptake inhibitor (SSRI). There have been reports of fetuses who were exposed to SSRI medications during the third trimester of pregnancy developing complications that required hospitalization, respiratory support, and/or tube feeding. These newborns experienced a number of symptoms, including:
 
  • Difficulty breathing
  • Seizures
  • Lack of oxygen in the blood
  • Feeding difficulties
  • Tremors
  • Irritability
  • Constant crying.
 
Also, babies exposed to SSRIs late during pregnancy are at increased risk for developing persistent pulmonary hypertension of the newborn (PPHN). PPHN is associated with significant complications and even death. Women who take SSRIs, including Sarafem, after week 20 of pregnancy have an increased risk of delivering a baby with PPHN.
 

Sarafem and Pregnancy: Summary

If you are pregnant or thinking of becoming pregnant while taking Sarafem, let your healthcare provider know. Your healthcare provider will consider both the benefits and risks of taking Sarafem during pregnancy before making a recommendation for your particular situation.
 
Pregnancy and Pain

Sarafem for PMDD

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