SNRI Withdrawal

SNRIs (serotonin-norepinephrine reuptake inhibitors) are known to cause withdrawal symptoms in those who quickly stop their medicine.
 

SNRI Withdrawal Symptoms

Certain SNRI withdrawal symptoms can include, but are not limited to:
 
  • Dizziness
  • Nausea
  • Headache
  • Unpleasant sensations (such as tingling or burning)
  • Vomiting
  • Irritability
  • Nightmares.
     
In most people, these SNRI withdrawal symptoms improve with time, without the need for any treatment.
 

Limiting SNRI Withdrawal

If you are going to be taken off of an SNRI, your healthcare provider may wean you off slowly to minimize the chances of developing SNRI withdrawal symptoms, although this is not always necessary.
 Sometimes, withdrawal symptoms are actually symptoms of depression returning. In this case, your healthcare provider may decide to put you back on an antidepressant medication.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;