SNRIs

Serotonin-Norepinephrine Reuptake Inhibitors

Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking an SNRI if you have:

Bipolar disorder or a family history of bipolar disorder (also known as manic depression)
A history of suicide attempts or suicidal thoughts
Had a recent heart attack or if you have unstable heart disease
Diabetic gastroparesis (a slowing of the digestive tract due to diabetes)
High blood pressure (hypertension) or low blood pressure (hypotension)
Seizures or epilepsy
Glaucoma (a condition of the eyes)
Liver disease, including liver failure or cirrhosis
Kidney problems, including kidney failure (renal failure)
Any allergies, including allergies to food, dyes, or preservatives.

Also, let your healthcare provider know if you:

Are pregnant or thinking of becoming pregnant (see SNRIs and Pregnancy)
Are breastfeeding (see SNRIs and Breastfeeding)
Drink alcohol regularly.

Be sure to tell your healthcare provider about all other medicines you may be taking, including prescription and nonprescription medications, vitamins, and herbal supplements.

(Click Precautions and Warnings With SNRIs for more information on this topic, including information on who should not take SNRIs.)

SNRI Overdose

People who take too much of an SNRI may have overdose symptoms that could include, but are not limited to:

Confusion
Diarrhea
Difficulty walking
Drowsiness
Feeling faint
Fever
Hallucination
Increased heart rate (tachycardia)
Muscle spasm
Seizures
Sweating
Vomiting.

If you happen to take an overdose, seek medical attention immediately.

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