Important Prescribing Guidelines for Sertraline

Sertraline Dosage for Premenstrual Dysphoric Disorder (PMDD)

The recommended starting dosage of sertraline for those with premenstrual dysphoric disorder (PMDD) is sertraline 50 mg once a day, throughout the entire menstrual cycle or just during the last two weeks of the cycle (before a woman's period starts), depending on the healthcare provider's instructions. The healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if side effects occur.

Sertraline Dosing and Children

The recommended starting dose of sertraline for children ages 6 to 12 with OCD is sertraline 25 mg once daily, while the starting dose of sertraline for adolescents ages 13 to 17 is sertraline 50 mg once daily.
The child's healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if sertraline side effects occur.

General Sertraline Dosing Information

Some general information concerning your dose of sertraline includes the following:
  • Sertraline comes in tablets and a liquid form. You take sertraline by mouth -- usually once a day.
  • Sertraline oral concentrate (the liquid form) must be diluted before each use. Measure the correct amount, then mix it with 4 ounces (half a cup) of water, ginger ale, lemon-lime soda, lemonade, or orange juice. Do not mix the sertraline oral concentrate with any other beverages. Also, mix the oral concentrate immediately before taking it -- do not prepare it far ahead of the time you intend to take it.
  • You can take sertraline with or without food. If sertraline bothers your stomach, try taking it with food.
  • If sertraline causes insomnia for you, try taking it in the morning. If sertraline makes you drowsy, try taking it before bedtime.
  • Take sertraline at the same time each day. This will help to maintain an even level of the drug in your blood.
  • Abruptly stopping medications like sertraline can result in withdrawal symptoms (see Zoloft Withdrawal for more information).
  • For sertraline to work properly, you have to take it as prescribed. Sertraline will not work if you take it differently than how your healthcare provider prescribed it.
  • If you are unsure about anything related to sertraline or your sertraline dosage, please talk to your doctor, nurse, or pharmacist. Do not stop taking sertraline without first discussing it with your healthcare provider.
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Sertraline Hydrochloride

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