Sertraline Dosing

For adults with depression or obsessive-compulsive disorder (OCD), sertraline dosing guidelines generally call for a dose of 50 mg once daily. The dose of sertraline usually used to treat panic disorder or social anxiety disorder usually starts at 25 mg once a day and then often increases to 50 mg daily. Sertraline dosing for children ages 6 to 12 with OCD typically involves a dose of 25 mg once a day.

An Introduction to Sertraline Dosing

The dose of sertraline hydrochloride (Zoloft®) your healthcare provider prescribes will vary depending on a number of factors, including:
 
  • Your age
  • The medical condition for which you are being treated
  • Other medical conditions you may have
  • Other medications you may be taking.
     
As is always the case, do not adjust your sertraline dose unless your healthcare provider specifically instructs you to do so.
 

Sertraline Dosing for Depression or Obsessive-Compulsive Disorder (OCD)

The recommended starting sertraline dose for people with depression or obsessive-compulsive disorder (OCD) is sertraline 50 mg once a day. The healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if side effects occur.
 

Sertraline Dosage for Panic Disorder, Post-traumatic Stress Disorder, or Social Anxiety Disorder

The recommended starting sertraline dose for people with
 panic disorder, post-traumatic stress disorder (PTSD), or social anxiety disorder is sertraline 25 mg once a day. After a week, your healthcare provider will likely increase the dose up to 50 mg of sertraline once a day. The healthcare provider may choose to increase the sertraline dosage if symptoms continue, or decrease the dose if side effects occur.
 
(Sertraline Dosing Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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