Side Effects of Sertraline

Some of the most common side effects of sertraline include nausea, insomnia, and diarrhea. Other side effects that may occur with the medication include such things as dry mouth, dizziness, and fatigue. While most sertraline side effects tend to be minor, there are some potentially serious problems that can occur while taking the medication. Contact your healthcare provider if you experience hallucinations, anxiety, or suicidal thoughts.

 

An Introduction to Side Effects of Sertraline

Sertraline hydrochloride (Zoloft®) is a prescription medication used to treat a number of conditions within the brain. As with any medicine, side effects are possible with sertraline; however, not everyone who takes it will experience side effects. In fact, most people tolerate the drug well. If sertraline side effects occur, in most cases, they are minor and either require no treatment or can be easily treated by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with sertraline. Your healthcare provider can discuss a more complete list of sertraline side effects with you.)
 

Sertraline Side Effects to Report

Some sertraline side effects, while occurring infrequently, are potentially serious and should be reported to your healthcare provider.
 These include but are not limited to:
 
  • Suicidal thoughts or behavior (see Zoloft and Suicide)
  • Anxiety, agitation, or panic attacks
  • Hostility or aggressiveness
  • Engaging in unusual or dangerous activities
  • Extreme elation or feeling of happiness that may switch back and forth with a depressed or sad mood
  • Other unusual changes in behavior
  • Hallucinations
  • Fast heart rate
  • Chest palpitations
  • Feelings of internal restlessness or jitteriness
  • Signs of an allergic reaction, including:
 
    • Unexplained rash
    • Hives
    • Itching
    • Unexplained swelling
    • Wheezing
    • Difficulty breathing or swallowing.
 
(Side Effects of Sertraline Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;