Drug Interactions With Trifluoperazine

Several medications can cause drug interactions with trifluoperazine, including barbiturates, certain seizure medications, and narcotics. These interactions can increase the risk of side effects, cause sedation, or alter the amounts of the medications in the blood, which may decrease their effectiveness. If drug interactions with trifluoperazine are a concern, your healthcare provider may adjust your dosages or monitor you more closely.

An Introduction to Drug Interactions With Trifluoperazine

 Trifluoperazine hydrochloride (Stelazine®) can potentially interact with a number of other medicines. Some of the medicines that may lead to drug interactions with trifluoperazine include:
 
  • Alcohol
 
  • Barbiturates, including:
o Amobarbital (Amytal®)
o Butalbital (Fioricet®, Fiorinal®)
o Pentobarbital (Nembutal®)
o Phenobarbital (Luminal®)
o Secobarbital (Seconal®)
  • Certain anticonvulsants, including:
o Fosphenytoin (Cerebyx®)
 
 
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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