Xanax Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when Xanax is combined with any of the drugs listed above.

 

Combining alcohol with Xanax can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. It is best to avoid alcohol while taking Xanax (see Xanax and Alcohol).

 

Combining an antidepressant with Xanax can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Additionally, many antidepressants can raise the level of Xanax in your blood, which further increases your risk of developing side effects. Make sure to talk with your healthcare provider before taking Xanax with an antidepressant, as you may need to be monitored more closely and may need a lower Xanax dose.

 

Combining an antipsychotic medication with Xanax can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk with your healthcare provider before taking Xanax with an antipsychotic medication.

 

Combining a barbiturate with Xanax can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk with your healthcare provider before taking Xanax with a barbiturate.

 

Taking Xanax with certain antibiotics or antifungals can raise the level of Xanax in your blood, increasing your risk of side effects. In general, Xanax should not be taken with these medications (especially ketoconazole or itraconazole).